NAD+

NAD+

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NAD+ (β-Nicotinamide Adenine Dinucleotide) supplied in 500 mg lyophilized vials with mannitol stabilizer. ≥99% purity, third-party tested. For in-vitro/ex-vivo research only. COA provided.

$99.00

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Quantity

500 MG

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Buy NAD+ (β-Nicotinamide Adenine Dinucleotide) – Research Vial 500 mg

GLPBulk supplies NAD+ (β-Nicotinamide Adenine Dinucleotide) as high-purity lyophilized research vials. Each batch is produced under controlled conditions and third-party verified (≥99% purity, HPLC/MS). A current COA is posted on this page.

Batch & Supply Format

  • ≥99% purity (third-party HPLC/MS)
  • Lyophilized NAD+ with mannitol stabilizer
  • 500 mg bulk-fill vial
  • Documented chain-of-custody & COA verification
  • U.S. domestic fulfillment

What Is NAD⁺?

NAD+ (β-Nicotinamide Adenine Dinucleotide) is a central metabolic coenzyme involved in redox reactions, mitochondrial activity, and cellular energetics. In research environments, NAD+ is studied for its role in:

  1. Electron Transport Chain Function—acting as a key hydride acceptor/donor
  2. Sirtuin Activation — supporting NAD+-dependent deacetylase activity
  3. Redox Cycling — maintaining cellular NAD+/NADH ratios

Supplied exclusively for laboratory research (in-vitro/ex-vivo). Not for administration to humans or animals.

Mechanistic Overview

  • Redox Cofactor: Central to oxidative and glycolytic energy pathways.
  • Mitochondrial Role: Supports enzymatic activity across complexes I & III.
  • Sirtuin Pathways: Required for SIRT1–SIRT7 activity in research models.
  • DNA Repair Signaling: Precursor substrate for PARP pathways in cell culture models.

Research Evidence Snapshot

Preclinical and biochemical literature examines NAD+ in mitochondrial energetics, metabolic signaling, and cellular stress responses. Researchers should reference primary publications for concentration-specific protocols and analytical methods.

NAD+ vs NMN vs NR

Feature NAD+ NMN Nicotinamide Riboside (NR)
Structure Dinucleotide Redox Cofactor Nucleotide precursor Riboside precursor
Direct Activity Immediately active in redox cycling Requires enzymatic conversion to NAD+ Requires conversion to NMN → NAD+
Research Focus Cellular energetics & redox function Biosynthetic pathway studies Metabolic signaling

Why GLPBulk

  • ≥99% purity: third-party HPLC/MS verified
  • Mannitol-Stabilized: optimized for bulk lyophilization
  • Reliable availability: consistent lot production
  • U.S. fulfillment: temperature-appropriate packaging
  • COA transparency: certificate included with each batch

Format & Handling

  • Form: Lyophilized powder (13 mm vial)
  • Fill Amount: 500 mg NAD+
  • Stabilizer: Mannitol included
  • Reconstitution (general lab practice): Add sterile water or suitable buffer; swirl gently; record final concentration
  • Research calculator: GLPBulk  Peptide Calculator

Product Specifications

  • Name: β-Nicotinamide Adenine Dinucleotide (NAD+)
  • Synonyms: NAD, β-NAD, DPN⁺
  • Molecular Formula: C21H27N7O14P2
  • Molecular Weight: ~663.4 g/mol
  • Purity: ≥99% (third-party HPLC/MS)
  • Additives: Mannitol (lyophilization stabilizer)
  • Use: In-vitro/ex-vivo research only

Storage & Stability

  • Unreconstituted: Store dry, protected from light
  • After Reconstitution: 2–8 °C; aliquot if long-term storage is needed
  • Shelf Life: 3–4 years (lyophilized)

Legal & Safety

All products are supplied for laboratory research use only. Not for human or veterinary administration. End users must follow applicable laws and institutional requirements. Purchase constitutes acceptance of these terms.

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